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CRDB_PT0015

Publication No.EP0861223
CRDB IDCRDB_PT0015
TitleProcess for the synthesis of curcumin-related compounds
CountryEurope
Publication Date02.09.1998
International Classification C07C 49/248
Application No.96937854
Applicant GENEPRINT INC
InventorKRACKOV MARK HARRY
Google Patent Link EP0861223
AbstractThe invention is directed to a process for the synthesis of curcumin and curcumin-related compounds by reacting the enol form of a 2,4-diketone with a monocarbocyclic aldehyde in the presence of an organic amine catalyst. The reactants are dissolved in a highly polar, aprotic organic solvent. The curcumin-related product is recovered in crystalline form by precipitation from the reaction mass and solvent recrystallization.