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CRDB_PT0028

Publication No.EP1494993
CRDB IDCRDB_PT0028
TitleNovel curcumin analogues and uses thereof
CountryEurope
Publication Date12.01.2005
International Classification C07C 69/76
Application No.3718072
Applicant UNIV NORTH CAROLINA
InventorLEE KUO-HSIUNG
Google Patent Link EP1494993
AbstractThe present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agents, particularly for the treatment of cancers such as colon, skin and prostate cancer and to induce androgen receptor antagonist activity in a subject afflicted with an androgen-related affliction. Examples of androgen-related afflictions include, but are not limited to, baldness, hirsutism, behavioral disorders, acne, and uninhibited spermatogenesis wherein inhibition of spermatogenesis is so desired.